This research aims to analyze on the land suitability, to study potential in urban area and the access by analyzing the space syntax in Prachinburi comprehensive plan that is the study area. The study was concluded that the suitable areas for residence and commerce were found along to Tatsanavitee Road and some along to Ratdamri Road , Prachin-Ta Kam, Khaew Phichit Road, Prachinnusorn Road. Consequently, most of the areas above are easily connected to the main road, also near the activities groups associating with the development area. Besides, the suitable areas for industry were found somewhere around Sakrityutthasin Road, some around the bypass and the highway no. 319. In addition, the suitable areas for agriculture were generally found all almost common areas; both the municipality and the surrounding areas but it is the highest density at the outskirts of the municipality. The cause may be the geography with Prachinburi River flowing through that area, so it is the important water source for agriculture. Hence, it makes these areas are high potential in agricultural development. However, there are still some areas that were reduced by the factor; some flooded areas are seriously damaged to areas in the town, Prachinburi. According to the data analysis, it conduces to the improvement of Prachinburi comprehensive plan.